CLASS I Drug recall · Reported 5 Nov 2014 · FDA Enforcement Report

Cubicin (daptomycin for injection) 500 mg, For Intravenous Use Only recalled

Cubist Pharmaceuticals is recalling Cubicin (daptomycin for injection) 500 mg, For Intravenous Use Only, distributed nationwide in the US. The recall was initiated on 8 Aug 2014 and the FDA has classified it as Class I.

Check your package

Lot, batch or date codesLot #'s: CDC203, Exp 12/2015; CDC207, Exp 01/2016; CDC213, Exp 02/2016; CDC217, Exp 03/2016; CDC226, Exp 04/2016; CDC234, CDC235, Exp 05/2016; CDC243, CDC246, Exp 07/2016.
Quantity recalled371,879 Vials

Check the lot number on your package against the affected lots. If it matches, contact the pharmacy that dispensed it or your prescriber before stopping any medication.

Recall details

Recall number
D-0229-2015
FDA event ID
67180
Recalling firm
Cubist Pharmaceuticals, Lexington, MA
Classification
Class I
Status
Terminated
Recall initiated
8 Aug 2014
FDA classified
30 Oct 2014
Reported
5 Nov 2014
Type
Voluntary: Firm initiated
Customers notified by
Press Release
Reason category
Particulate Matter

Timeline

8 Aug 2014Recall initiated by company
30 Oct 2014Classified by FDA+83 days
5 Nov 2014Published in enforcement report+6 days

Companies usually start a recall weeks before the FDA classifies and publishes it; the gap above is that lag.

Reason for recall

Presence of Particulate Matter: Foreign particulate matter (tiny black specs) were observed at the bottom of the vial following reconstitution.

Product as listed by the FDA

CUBICIN (daptomycin for injection) 500 mg, For Intravenous Use Only, Rx Only, Single use Vial, Manufactured for: Cubist Pharmaceuticals Inc., Lexington, MA 02421, USA, NDC 67919-011-01

Where it was distributed

Nationwide and Puerto Rico.

Nationwide Puerto Rico

Questions about this recall

Why was it recalled?

Presence of Particulate Matter: Foreign particulate matter (tiny black specs) were observed at the bottom of the vial following reconstitution.

Which lots are affected?

Lot #'s: CDC203, Exp 12/2015; CDC207, Exp 01/2016; CDC213, Exp 02/2016; CDC217, Exp 03/2016; CDC226, Exp 04/2016; CDC234, CDC235, Exp 05/2016; CDC243, CDC246, Exp 07/2016.

Where was it sold?

Nationwide and Puerto Rico.

What should I do if I have it?

Check the lot number on your package against the affected lots. If it matches, contact the pharmacy that dispensed it or your prescriber before stopping any medication.

What does Class I mean?

Class I is the most serious FDA recall category: there is a reasonable probability that using the product will cause serious health consequences or death.

Read the official FDA notice · Source record retrieved 26 Sep 2026. The FDA describes openFDA data as unvalidated; the official notice takes precedence. This page reports the record and gives no medical advice.

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