CLASS I Drug recall · Reported 30 Jan 2013 · FDA Enforcement Report

Trastuzumab Kit containing 1 vial Trastuzumab recalled by Genentech

Genentech is recalling Trastuzumab Kit containing 1 vial Trastuzumab (nominal content: 440 mg), distributed nationwide in the US. The recall was initiated on 30 Jul 2012 and the FDA has classified it as Class I.

Check your package

Lot, batch or date codesLot #: 454138, Exp 07/14 (containing Trastuzumab Lot #: 886618, Exp 12/14; and Bacteriostatic Water for Injection, USP Lot #: 08-368-DK-01, Exp 07/14)
Quantity recalled2,140 kits

Check the lot number on your package against the affected lots. If it matches, contact the pharmacy that dispensed it or your prescriber before stopping any medication.

Recall details

Recall number
D-135-2013
FDA event ID
63258
Recalling firm
Genentech, South San Francisco, CA
Classification
Class I
Status
Terminated
Recall initiated
30 Jul 2012
FDA classified
22 Jan 2013
Reported
30 Jan 2013
Type
Voluntary: Firm initiated
Customers notified by
E-Mail
Reason category
Particulate Matter

Timeline

30 Jul 2012Recall initiated by company
22 Jan 2013Classified by FDA+176 days
30 Jan 2013Published in enforcement report+8 days

Companies usually start a recall weeks before the FDA classifies and publishes it; the gap above is that lag.

Reason for recall

Presence of Particulate Matter: One lot of Bacteriostatic Water for Injection, USP diluent vials that were packed with Trastuzumab Kits for investigational use has the potential to contain glass particulates.

Product as listed by the FDA

Trastuzumab Kit containing 1 vial Trastuzumab (nominal content: 440 mg); 1 20 mL multiple dose vial Bacteriostatic Water for Injection, USP (1.1% benzyl alcohol), Manufactured by Hospira, Inc., for Genentech, Inc., South San Francisco, CA 94080-4990, NDC 50242-903-69; and 1 Reconstitution Instructions per kit; Investigation Use only, Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080-4990.

Where it was distributed

Nationwide

Nationwide

Questions about this recall

Is Trastuzumab Kit containing 1 vial Trastuzumab (nominal content: 440 mg) recalled?

Yes. Genentech recalled Trastuzumab Kit containing 1 vial Trastuzumab (nominal content: 440 mg) on 30 Jul 2012. The recall is Class I and its status is Terminated. Recall number D-135-2013.

Why was it recalled?

Presence of Particulate Matter: One lot of Bacteriostatic Water for Injection, USP diluent vials that were packed with Trastuzumab Kits for investigational use has the potential to contain glass particulates.

Which lots are affected?

Lot #: 454138, Exp 07/14 (containing Trastuzumab Lot #: 886618, Exp 12/14; and Bacteriostatic Water for Injection, USP Lot #: 08-368-DK-01, Exp 07/14)

Where was it sold?

Nationwide

What should I do if I have it?

Check the lot number on your package against the affected lots. If it matches, contact the pharmacy that dispensed it or your prescriber before stopping any medication.

What does Class I mean?

Class I is the most serious FDA recall category: there is a reasonable probability that using the product will cause serious health consequences or death.

Read the official FDA notice · Source record retrieved 21 Sep 2026. The FDA describes openFDA data as unvalidated; the official notice takes precedence. This page reports the record and gives no medical advice.

More recalls from Genentech

All 11
ReportedClassRecallCompanyReasonWhere
DrugCLASS IICathflo activase (Alteplase), 2mg vials recalled by GenentechCathflo ActivaseGenentechSterilityNationwide
DrugCLASS IIISusvimo (ranibizumab injection), 100mg/mL recalled by GenentechSusvimoGenentechOtherNationwide
DrugCLASS IIXolair (omalizumab) Injection, 150 mg/, 1 prefilled syringe recalledXolairGenentechPotency & AssayNationwide
DrugCLASS IIIEvrysdi (risdiplam) for oral solution recalled by GenentechGenentechOtherNationwide
DrugCLASS IIIKlonopin (clonazepam) recalled by GenentechGenentechOtherNationwide