CLASS II Drug recall · Reported 9 Sep 2015 · FDA Enforcement Report

Bi-Est (estriol,estradiol), Progesterone Vaginal Suppository recalled

South Coast Specialty Compounding is recalling Bi-Est (estriol,estradiol), Progesterone Vaginal Suppository, distributed nationwide in the US. The recall was initiated on 23 Apr 2015 and the FDA has classified it as Class II.

Check your package

Lot, batch or date codesLot #: 01052015@12 01132015@2 01132015@36 01132015@37 01152015@4 01162015@66 01202015@34 02112015@11 02112015@11 02252015@34 10312014@13 11042014@42 11052014@46 11072014@21 11122014@43 11122014@45 11182014@15 11192014@41 11242014@29 11262014@14 12022014@13 12102014@4 12192014@40 12222014@18 Exp. 07/15
Quantity recalled24 suppositories (24 prescriptions)

Check the lot number on your package against the affected lots. If it matches, contact the pharmacy that dispensed it or your prescriber before stopping any medication.

Recall details

Recall number
D-1415-2015
FDA event ID
71078
Recalling firm
South Coast Specialty Compounding, Irvine, CA
Classification
Class II
Status
Terminated
Recall initiated
23 Apr 2015
FDA classified
2 Sep 2015
Reported
9 Sep 2015
Type
Voluntary: Firm initiated
Customers notified by
Letter
Reason category
Other Reasons

Timeline

23 Apr 2015Recall initiated by company
2 Sep 2015Classified by FDA+132 days
9 Sep 2015Published in enforcement report+7 days

Companies usually start a recall weeks before the FDA classifies and publishes it; the gap above is that lag.

Reason for recall

Penicillin Cross Contamination: Multiple finished products potentially contaminated with penicillin.

Product as listed by the FDA

Bi-Est (estriol,estradiol), Progesterone Vaginal Suppository, Rx only, Manufactured by Park Compounding, Irvine, CA

Where it was distributed

Nationwide.

Nationwide

Questions about this recall

Why was it recalled?

Penicillin Cross Contamination: Multiple finished products potentially contaminated with penicillin.

Which lots are affected?

Lot #: 01052015@12 01132015@2 01132015@36 01132015@37 01152015@4 01162015@66 01202015@34 02112015@11 02112015@11 02252015@34 10312014@13 11042014@42 11052014@46 11072014@21 11122014@43 11122014@45 11182014@15 11192014@41 11242014@29 11262014@14 12022014@13 12102014@4 12192014@40 12222014@18 Exp. 07/15

Where was it sold?

Nationwide.

What should I do if I have it?

Check the lot number on your package against the affected lots. If it matches, contact the pharmacy that dispensed it or your prescriber before stopping any medication.

What does Class II mean?

Class II means the product may cause temporary or medically reversible health problems, or the probability of serious harm is remote.

Read the official FDA notice · Source record retrieved 26 Sep 2026. The FDA describes openFDA data as unvalidated; the official notice takes precedence. This page reports the record and gives no medical advice.

Other products in this recall event

14 other products · FDA event 71078
ReportedClassRecallCompanyReasonWhere
CLASS IIEstradiol, Estriol capsules recalled by South Coast SpecialtySouth Coast Specialty CompoundingOtherNationwide
CLASS IIBi-Est 80:20 Progesterone (estriol,estradiol, progesterone) capsules recalledSouth Coast Specialty CompoundingOtherNationwide
CLASS IIBi-Est (estriol,estradiol), Progesterone, Testosterone cream recalledSouth Coast Specialty CompoundingOtherNationwide
CLASS IIMeloxicam capsules, 12 mg recalled by South Coast SpecialtySouth Coast Specialty CompoundingOtherNationwide
CLASS IIChorionic Gonadotropin/ Hydroxocobalamin Lyophilized Powder recalledSouth Coast Specialty CompoundingOtherNationwide
CLASS IIMethyl Folate Lyophilized Powder for Injection, 20 mg per vial recalledSouth Coast Specialty CompoundingOtherNationwide
CLASS IIBi-Est (estriol,estradiol) Testosterone cream recalledSouth Coast Specialty CompoundingOtherNationwide
CLASS IILeucovorin Calcium capsules, 10 mg recalled by South Coast SpecialtySouth Coast Specialty CompoundingOtherNationwide
CLASS IIArtesunate Lyophilized Powder for Injection, 60 mg per vial recalledSouth Coast Specialty CompoundingOtherNationwide
CLASS IIEstriol,Estradiol cream recalled by South Coast SpecialtySouth Coast Specialty CompoundingOtherNationwide
CLASS IIBi-Est (estriol,estradiol), Progesterone, DHEA, Testosterone drops recalledSouth Coast Specialty CompoundingOtherNationwide
CLASS IITri-Est 80:10:10 Progesterone (estriol, estradiol, estrone recalledSouth Coast Specialty CompoundingOtherNationwide
CLASS IIEstradiol, Estriol, Progesterone capsules recalledSouth Coast Specialty CompoundingOtherNationwide
CLASS IIEstradiol cream recalled by South Coast SpecialtySouth Coast Specialty CompoundingOtherNationwide

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