CLASS II Drug recall · Reported 2 Feb 2022 · FDA Enforcement Report

Metformin Hydrochloride Extended-Release Tablets, USP 750 mg HDPE recalled

Viona Pharmaceuticals is recalling Metformin Hydrochloride Extended-Release Tablets, USP 750 mg HDPE. The recall was initiated on 27 Dec 2021 and the FDA has classified it as Class II.

Check your package

Lot, batch or date codesM008130 06/2022, M008131 06/2022, M008132 06/2022, M008133 06/2022, M010080 07/2022, M010081 07/2022, M011029 08/2022, M011030 08/2022, M011031 08/2022, M011032 08/2022, M011304 08/2022, M013394 09/2022, M013395 09/2022, M013396 09/2022, M013966 09/2022, M013967 09/2022, M100831 12/2022, M100832 12/2022, M100833 01/2023, M100834 01/2023, M101267 01/2023, M102718 01/2023, M102719 01/2023
NDC72578-035, 72578-036
Quantity recalled23,8416/100 count bottles

Check the lot number on your package against the affected lots. If it matches, contact the pharmacy that dispensed it or your prescriber before stopping any medication.

Recall details

Recall number
D-0392-2022
FDA event ID
89305
Recalling firm
Viona Pharmaceuticals, Cranford, NJ
Manufacturer
Viona Pharmaceuticals Inc
Classification
Class II
Status
Terminated
Recall initiated
27 Dec 2021
FDA classified
21 Jan 2022
Reported
2 Feb 2022
Type
Voluntary: Firm initiated
Customers notified by
Letter
Reason category
Nitrosamine Impurity

Timeline

27 Dec 2021Recall initiated by company
21 Jan 2022Classified by FDA+25 days
2 Feb 2022Published in enforcement report+12 days

Companies usually start a recall weeks before the FDA classifies and publishes it; the gap above is that lag.

Reason for recall

CGMP Deviations- Detection of N-Nitrosodimethylamine (NDMA) levels in excess of the Acceptable Daily Intake Limit.

Nitrosamines are impurities that can form during drug manufacturing or storage. Above the FDA acceptable intake limit, long-term exposure may raise cancer risk. The FDA advises patients to keep taking the medicine until they have a replacement.

Product as listed by the FDA

Metformin Hydrochloride Extended-Release Tablets, USP 750 mg, 100 count HDPE bottles NDC# 72578-036-01

Where it was distributed

Product was distributed to 17 wholesalers who further distributed the product to 85 locations.

Questions about this recall

Is Metformin Hydrochloride Extended-Release Tablets, USP 750 mg HDPE recalled?

Yes. Viona Pharmaceuticals recalled Metformin Hydrochloride Extended-Release Tablets, USP 750 mg HDPE on 27 Dec 2021. The recall is Class II and its status is Terminated. Recall number D-0392-2022.

Why was it recalled?

CGMP Deviations- Detection of N-Nitrosodimethylamine (NDMA) levels in excess of the Acceptable Daily Intake Limit.

Which lots are affected?

M008130 06/2022, M008131 06/2022, M008132 06/2022, M008133 06/2022, M010080 07/2022, M010081 07/2022, M011029 08/2022, M011030 08/2022, M011031 08/2022, M011032 08/2022, M011304 08/2022, M013394 09/2022, M013395 09/2022, M013396 09/2022, M013966 09/2022, M013967 09/2022, M100831 12/2022, M100832 12/2022, M100833 01/2023, M100834 01/2023, M101267 01/2023, M102718 01/2023, M102719 01/2023

Where was it sold?

Product was distributed to 17 wholesalers who further distributed the product to 85 locations.

What should I do if I have it?

Check the lot number on your package against the affected lots. If it matches, contact the pharmacy that dispensed it or your prescriber before stopping any medication.

What does Class II mean?

Class II means the product may cause temporary or medically reversible health problems, or the probability of serious harm is remote.

Read the official FDA notice · Source record retrieved 21 Sep 2026. The FDA describes openFDA data as unvalidated; the official notice takes precedence. This page reports the record and gives no medical advice.

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