CLASS II Drug recall · Reported 8 Feb 2017 · FDA Enforcement Report

Methadone Hydrochloride Oral Concentrate, USP 10 mg/mL C-II, a.) recalled

VistaPharm is recalling Methadone Hydrochloride Oral Concentrate, USP 10 mg/mL C-II, a.) (, distributed nationwide in the US. The recall was initiated on 18 Jan 2017 and the FDA has classified it as Class II.

Check your package

Lot, batch or date codesa). Lot No. 416600 (Exp. 09/17) b). Lot No.449100 , 447500 (Exp. 04/18), 421800 (Exp. 10/17), 418600 (Exp. 09/17), 408700 (Exp. 06/17), 411900 (Exp. 07/17), 413800 (Exp. 08/17), 416500 (Exp. 09/17), 408500 (Exp. 06/17), 389800 (Exp. 01/17), 429900 (Exp. 12/17), 406300, 406100 (Exp. 05/17), 429700 (Exp. 12/17), 427300, 427100, 425900 (11/17)
NDC66689-694, 66689-695
Quantity recalled127,193 bottles

Check the lot number on your package against the affected lots. If it matches, contact the pharmacy that dispensed it or your prescriber before stopping any medication.

Recall details

Recall number
D-0465-2017
FDA event ID
75650
Recalling firm
VistaPharm, Largo, FL
Manufacturer
VistaPharm, LLC
Classification
Class II
Status
Terminated
Recall initiated
18 Jan 2017
FDA classified
2 Feb 2017
Reported
8 Feb 2017
Type
Voluntary: Firm initiated
Customers notified by
Two or more of the following: Email, Fax, Letter, Press Release, Telephone, Visit
Reason category
Sterility

Timeline

18 Jan 2017Recall initiated by company
2 Feb 2017Classified by FDA+15 days
8 Feb 2017Published in enforcement report+6 days

Companies usually start a recall weeks before the FDA classifies and publishes it; the gap above is that lag.

Reason for recall

CGMP Deviations: Purified water used to manufacture the drug products may have been contaminated with Burkholderia cepacia.

A sterility recall means a product that must be sterile, such as an injection or eye drop, may be contaminated. Using a non-sterile product can cause serious infection.

Product as listed by the FDA

Methadone Hydrochloride Oral Concentrate, USP 10 mg/mL C-II, a.) 1 fl. oz. (30 mL), 12 bottles per case (NDC No. 66689-695-30), b). 1 liter (1000 mL), 4 bottles per case, (NDC No. 66689-695-79), Rx only, Manufactured by VistaPharm, Largo, FL 33771.

Where it was distributed

Nationwide

Nationwide

Questions about this recall

Why was it recalled?

CGMP Deviations: Purified water used to manufacture the drug products may have been contaminated with Burkholderia cepacia.

Which lots are affected?

a). Lot No. 416600 (Exp. 09/17) b). Lot No.449100 , 447500 (Exp. 04/18), 421800 (Exp. 10/17), 418600 (Exp. 09/17), 408700 (Exp. 06/17), 411900 (Exp. 07/17), 413800 (Exp. 08/17), 416500 (Exp. 09/17), 408500 (Exp. 06/17), 389800 (Exp. 01/17), 429900 (Exp. 12/17), 406300, 406100 (Exp. 05/17), 429700 (Exp. 12/17), 427300, 427100, 425900 (11/17)

Where was it sold?

Nationwide

What should I do if I have it?

Check the lot number on your package against the affected lots. If it matches, contact the pharmacy that dispensed it or your prescriber before stopping any medication.

What does Class II mean?

Class II means the product may cause temporary or medically reversible health problems, or the probability of serious harm is remote.

Read the official FDA notice · Source record retrieved 26 Sep 2026. The FDA describes openFDA data as unvalidated; the official notice takes precedence. This page reports the record and gives no medical advice.

Other products in this recall event

10 other products · FDA event 75650

This product is part of a recall event; the main page for the event is Metoclopramide Oral Solution, USP 10 mg/ dose cups recalled.

More recalls from VistaPharm

All 36

Other Methadone recalls

All 9