CLASS I ONGOING Drug recall · Reported 2 Sep 2026 · FDA Enforcement Report

Tyenne (tocilizumab-aazg) Injection, 400 mg/ (20 mg/mL) vial recalled

Fresenius Kabi USA is recalling Tyenne (tocilizumab-aazg) Injection, 400 mg/ (20 mg/mL) vial, distributed nationwide in the US. The recall was initiated on 10 Aug 2026 and the FDA has classified it as Class I.

Check your package

Lot, batch or date codesLot: 16UI07, Exp 08/31/2028
NDC65219-590, 65219-592, 65219-594
Quantity recalled4,643 20mL-vials

Check the lot number on your package against the affected lots. If it matches, contact the pharmacy that dispensed it or your prescriber before stopping any medication.

Recall details

Recall number
D-0827-2026
FDA event ID
99603
Recalling firm
Fresenius Kabi USA, Lake Zurich, IL
Brand
Tyenne
Manufacturer
Fresenius Kabi USA, LLC
Classification
Class I
Status
Ongoing
Recall initiated
10 Aug 2026
FDA classified
1 Sep 2026
Reported
2 Sep 2026
Type
Voluntary: Firm initiated
Customers notified by
Two or more of the following: Email, Fax, Letter, Press Release, Telephone, Visit
Reason category
Particulate Matter

Timeline

10 Aug 2026Recall initiated by company
1 Sep 2026Classified by FDA+22 days
2 Sep 2026Published in enforcement report+1 day

Companies usually start a recall weeks before the FDA classifies and publishes it; the gap above is that lag.

Reason for recall

Presence of particulate matter:An internal investigation at the firm found the product to contain glass particles.

Product as listed by the FDA

Tyenne (tocilizumab-aazg) Injection, 400 mg/20 mL (20 mg/mL), 20 mL vial, Rx Only, Manufactured by Fresenius Kabi USA, LLC, Lake Zurich, Illinois, 60047, NDC 65219-594-20.

Where it was distributed

Nationwide in the USA

Nationwide

Questions about this recall

Why was it recalled?

Presence of particulate matter:An internal investigation at the firm found the product to contain glass particles.

Which lots are affected?

Lot: 16UI07, Exp 08/31/2028

Where was it sold?

Nationwide in the USA

What should I do if I have it?

Check the lot number on your package against the affected lots. If it matches, contact the pharmacy that dispensed it or your prescriber before stopping any medication.

What does Class I mean?

Class I is the most serious FDA recall category: there is a reasonable probability that using the product will cause serious health consequences or death.

Read the official FDA notice · Source record retrieved 26 Sep 2026. The FDA describes openFDA data as unvalidated; the official notice takes precedence. This page reports the record and gives no medical advice.

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