CLASS II Device recall · Reported 30 Dec 2015 · FDA Enforcement Report

Factor VIII Chromogenic Assay recalled by Siemens Healthcare Diagnostics

Siemens Healthcare Diagnostics is recalling Factor VIII Chromogenic Assay, distributed in Massachusetts. The recall was initiated on 19 Nov 2015 and the FDA has classified it as Class II.

Check your package

Lot, batch or date codesLot Number 44637, exp. 2016-11-30
Quantity recalledDomestic: 52 kits, Foreign: 623 kits

Stop using the device if the notice says to, and contact the manufacturer or your healthcare provider for the correction or replacement.

Recall details

Recall number
Z-0468-2016
FDA event ID
72752
Recalling firm
Siemens Healthcare Diagnostics, Tarrytown, NY
Classification
Class II
Status
Terminated
Recall initiated
19 Nov 2015
FDA classified
22 Dec 2015
Reported
30 Dec 2015
Type
Voluntary: Firm initiated
Customers notified by
Letter
Reason category
Potency & Assay

Timeline

19 Nov 2015Recall initiated by company
22 Dec 2015Classified by FDA+33 days
30 Dec 2015Published in enforcement report+8 days

Companies usually start a recall weeks before the FDA classifies and publishes it; the gap above is that lag.

Reason for recall

Factor VIII Chromogenic Assay Lot 44637 is showing an increased occurrence of irregular curves when used for measurement on Sysmex CA-1500, CA-7000, CS-2000i, CS-2100i, CS-5100 Systems. This could lead, under certain circumstances, to an erroneously increased result with a Factor VIII Chromogenic Assay.

Potency and specification recalls happen when a batch tests outside its approved limits for strength, purity or dissolution, which can mean the dose delivered is higher or lower than labelled.

Product as listed by the FDA

Factor VIII Chromogenic Assay, REF/Catalog No. B4238-40, Siemens Material Number (SMN) 10445729, IVD. --- CLASSIFICATION NAME: Test, Qualitative and Quantitative Factor Deficiency

Where it was distributed

Worldwide Distribution - US Distribution to the state of : Massachusetts and to the countries of : Austria, Czech Republic, France, Germany, Hungary, Italy, Poland, Serbia, Spain and Sweden.

Massachusetts

Questions about this recall

Why was it recalled?

Factor VIII Chromogenic Assay Lot 44637 is showing an increased occurrence of irregular curves when used for measurement on Sysmex CA-1500, CA-7000, CS-2000i, CS-2100i, CS-5100 Systems. This could lead, under certain circumstances, to an erroneously increased result with a Factor VIII Chromogenic Assay.

Which lots are affected?

Lot Number 44637, exp. 2016-11-30

Where was it sold?

Worldwide Distribution - US Distribution to the state of : Massachusetts and to the countries of : Austria, Czech Republic, France, Germany, Hungary, Italy, Poland, Serbia, Spain and Sweden.

What should I do if I have it?

Stop using the device if the notice says to, and contact the manufacturer or your healthcare provider for the correction or replacement.

What does Class II mean?

Class II means the product may cause temporary or medically reversible health problems, or the probability of serious harm is remote.

Read the official FDA notice · Source record retrieved 26 Sep 2026. The FDA describes openFDA data as unvalidated; the official notice takes precedence. This page reports the record and gives no medical advice.

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